Cuauhtitlan (Mdz26r)

Frances Berdan and Patricia Anawalt suggest that the head represents "the black and white mask of the goddess Tlazolteotl ('Filth-Deity')," with its "cotton headband with two cotton fillets, a diagnostic characteristic of this goddess (see the Codex Borbonicus 1974:13)." Perhaps this female divine force has a special association with this particular Cuauhtitlan.

The Codex Mendoza has two additional representations of Cuauhtitlan, both involving trees with teeth. Gordon Whittaker (Deciphering Aztec Hieroglyphs, 2021, 102) has discovered that the full set of teeth (top and bottom) are often used, as here, when there is a ligature (-ti-) before the locative suffix -tlan, resulting in -titlan. This example supports the case. Advanced searches for glyphs ending in -tlan and ending in -titlan will provide data showing a somewhat mixed result, but there is a tendency toward what Whittaker suggests.
It is worth noting that this place name uses the -titlan postposition on the stem that once had the -tl absolutive (cuahuitl, tree). Whereas, the place name Cuauhtlan uses the -tlan postposition on the stem that once had the -tli absolutive (cuauhtli, eagle).